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Congenital Heart Defect Incidence Has Decreased in Down Syndrome Patients
June 03, 2016

Atrioventicular septal defect, ventricular septal defect, and atrial septal defect are among the most common diagnoses.
HealthDay News – For infants diagnosed with Down syndrome there has been a reduction in the risk of complex congenital heart defects, according to a study published online June 1 in Pediatrics.
Sofie Bergström, from the Karolinska Institutet in Stockholm, and colleagues conducted a population-based cohort study based on national health registers, including 2588 infants with Down Syndrome. They calculated the risk ratios for congenital heart defects per 3-year period, after adjustment for multiple factors.
« Complex congenital heart defects have become less common in infants diagnosed with Down syndrome, » the authors wrote.
References
- Bergstrom S, Carr H, Petersson G, et al. Trends in congenital heart defects in infants with Down syndrome. Pediatrics. 2016;138(1):e20160123. doi: 10.1542/peds.2016-0123.
- Riehle-Colarusso T, Oster ME. Down syndrome: changing cardiac phenotype? Pediatrics. 2016;138(1):e20161223. doi: 10.1542/peds.2016-0123.