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Congenital Heart Defect Incidence Has Decreased in Down Syndrome Patients
June 03, 2016
HealthDay News – For infants diagnosed with Down syndrome there has been a reduction in the risk of complex congenital heart defects, according to a study published online June 1 in Pediatrics.
Sofie Bergström, from the Karolinska Institutet in Stockholm, and colleagues conducted a population-based cohort study based on national health registers, including 2588 infants with Down Syndrome. They calculated the risk ratios for congenital heart defects per 3-year period, after adjustment for multiple factors.
« Complex congenital heart defects have become less common in infants diagnosed with Down syndrome, » the authors wrote.
- Bergstrom S, Carr H, Petersson G, et al. Trends in congenital heart defects in infants with Down syndrome. Pediatrics. 2016;138(1):e20160123. doi: 10.1542/peds.2016-0123.
- Riehle-Colarusso T, Oster ME. Down syndrome: changing cardiac phenotype? Pediatrics. 2016;138(1):e20161223. doi: 10.1542/peds.2016-0123.